The Manufacturing Associate will perform molecular biology workflows and operate robotic equipment to manufacture custom gene products. They are responsible for maintaining accurate documentation, following SOPs, and ensuring process consistency in a high-throughput environment.
Requirements overview
Candidates should have a Bachelor's or Associate's degree in a biological or chemical field, though relevant laboratory experience will be considered. Proficiency in molecular biology techniques and familiarity with manufacturing environments are essential.
Key skills
Molecular biologyPCRDNA quantitationDNA purificationRobotic laboratory equipmentBioanalyzersCentrifugesSealersThermocyclersSpectrometersHPLCNext Gen SequencingBatch recordsLean manufacturingDocumentationTroubleshooting
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Twist Bioscience is a synthetic biology company based in South San Francisco, California. The company has developed a proprietary silicon-based manufacturing process for the production of synthetic DNA.
Twist Bioscience serves Life Science researchers who are changing the world for the better. Coming from diverse fields of medicine, agriculture, and industrial chemicals, scientists use our synthetic genes, oligo pools, biopharma services, and NGS target enrichment to better lives and improve the sustainability of the planet.
Twist Bioscience is uniquely positioned to help accelerate these efforts by providing precision at a scale that is otherwise unavailable. Our technology overcomes inefficiencies and enables cost-effective, rapid, precise, high-throughput DNA synthesis and sequencing. We offer both the quality and quantity researchers need now to rapidly realize opportunities ahead.
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We are looking for motivated, enthusiastic individuals to join our Twist Bioscience Operations Team in San Francisco. The Manufacturing Associate will perform basic molecular biology workflows in a highly automated, high-throughput manner and will be responsible for the manufacture and analysis of a variety of custom gene products across Twist Bioscience’s proprietary process workflow to meet the Twist production forecast and timelines.
The ideal candidate will be driven and will do what it takes to keep manufacturing on track in a fast paced start-up environment. The Manufacturing Associate will be responsible for the production of custom gene based products and/or various intermediates according to established SOPs and complete manufacturing batch records to contribute to the daily production schedule.
Roles and Responsibilities include but are not limited to
Manufacture high quality bespoke variant library products in a custom MFG lab according to established SOPs.
Daily use of traditional molecular biology processes and techniques especially PCR, DNA quantitation and handling, DNA purification
Operation of robotic laboratory equipment and traditional lab equipment (bioanalyzers, centrifuges, sealers, thermocyclers, spectrometers, HPLCs, Next Gen Sequencing etc.)
Support evaluation and testing of new molecular biology approaches for library fabrication
Maintaining thorough, accurate and detailed documentation of all work produced in batch records, databases or other acceptable formats including problems and deviations
Updating and writing work instructions and documentation
Ability to work independently and in a safe manner
Attention to details for process consistency
Documentation, troubleshooting and addressing process deviations
Packaging products
Ability to work in an ISO, GMP, LEAN mfg environment and follow the lean manufacturing concepts
Daily completion of assigned tasks to keep MFG on track
Key Skills/Qualifications
Bachelors/ Associates degree in biology, chemistry, biochemistry, molecular biology: degree preferred but will consider candidates with relevant laboratory experience
Familiarity or prior experience in a manufacturing environment
Good written and verbal skills
Attention to details
Good computer skills and comfort in using computers for all aspects of MFG, experience with excel and word, Jira/Confluence, web based or similar programs
Typical Working Conditions are:
Team based laboratory environment.
Working in controlled laboratory environment
Must be able to stand for long periods of time while performing duties.
Must be able to work safely with chemicals and hazardous materials.
Must be able to lift up to 20 lbs.
Must be able to work outside of regular work hours/ work a flexible shift as needed
About Twist Bioscience
Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.
At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.
Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.
San Francisco applicants: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
San Francisco Bay Area Pay Range
$21—$25 USD