Research Associate - Open Rank - Wolfe Lab

Research Associate - Open Rank - Wolfe Lab Minimum Salary US-MA-Worcester Job Location 1 day ago (10/23/2026 11:20 AM) Requisition Number 2026-52078 # of Openings 1 Posted Date Day Shift Exempt Exempt/Non-Exempt Status Non Union Position -W60- Non Unit Professional Position Type Full-Time Min USD $40,000.00/Yr. Max USD $73,000.00/Yr. Overview POSITION SUMMARY: Under the direction of the Principal Investigator (PI) or designee, the Research Associate provides operational support to the laboratory. The Research Associate will perform research experiments as defined by the PI. This is an open-rank posting (there are 4 levels of Research Associate) - candidates will be hired into the level commensurate with their experience. Responsibilities ESSENTIAL FUNCTIONS: Research Associate I: Perform laboratory experiments and may be responsible for a single research project. Utilize all software relevant to experiment and equipment used. Interpret data, form conclusions and decide on next steps under the direction of the PI or designee. Maintain accurate records, may modify protocols with the approval of the PI or designee. Review literature, publications and grants relevant to assigned projects. Record results according to established lab, sponsor & university protocol Assist with performing data analysis and/or mathematical computations. Maintain a detailed lab notebook according to lab practice. Present findings at lab/group meetings Monitor laboratory supply levels and order as noted. Prepare and label buffers, media, solutions, etc. Assist with and comply with all safety regulation and infection control standards. Train on IACUC, IRB, EHS, Radiation safety protocols Comply with all applicable state, federal university, and sponsor policies and agreements. Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions. Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab. Perform other duties as required. Research Associate II: Duties noted above plus: May assist with the training of new lab personnel. Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab. May assist with drafting manuscript sessions. Research Associate III: Duties noted above plus: Perform complex laboratory experiments and may be responsible for one or more independent research projects. Perform in-depth data analysis and/or mathematical computations. Compile and analyze data and present it in a format suitable for publication according to PI specifications. May oversee laboratory supply levels and order as needed; negotiate with suppliers to optimize available resources. Monitor laboratory equipment service contracts and monitor maintenance on laboratory equipment. May manage general operations of the laboratory, including lab personnel, procedures, and projects. May create new protocols and/or modify defined protocols, as necessary, and with the approval of the PI. Prioritize and perform several tasks or procedures simultaneously with attention to detail. Perform duties and experiments with independence. Provide training of new lab personnel. May monitor laboratory spending in accordance with budget guidelines provided by PI or designee. May assist with budget and/or operational aspects of grant and contract funding. Research Associate IV: Duties noted above plus: This position will contribute significantly to the management of the research program and will be involved in multiple aspects of the research projects and lab maintenance activities. Independently design and perform multiple complex laboratory experiments. Interpret data, form conclusions, and decide on next steps with a high degree of independence. Maintain laboratory supply levels and order as noted. Manage laboratory equipment service contracts and coordinate maintenance on laboratory equipment. Monitor and enforce all safety regulations and infection control standards. Identify and write standard operation procedures in compliance to EHS regulation specific for the lab Train on IACUC, EHS, Radiation safety protocols Manage daily operations of the laboratory, including lab personnel, procedures, and projects. Identify problems and challenges, propose resolutions, implement appropriate solutions. Develop and implement new protocols and/or modify defined protocols, as necessary, and with the approval of the PI Mentor and train lab personnel on proper lab conduct and techniques. Manage laboratory spending in accordance with budget guidelines provided by PI or designee. Assist with budget and/or operational aspects of grant and contract proposals. Negotiate with vendors to optimize available resources. Contribute independently to writing sections for manuscripts and grants. Direct the activities of research support staff. Perform other duties as required. Qualifications REQUIRED QUALIFICATIONS: Research Associate I Bachelor’s degree in Biological or Natural Science, or equivalent experience Basic understanding of lab safety and protocols Knowledge of Microsoft Office products Ability to analyze data in a quantitative and objective manner. Ability to work in a team environment. Research Associate II Requirements noted for RA I plus: 18 months of relevant research experience with a Bachelor’s Degree in Biological or Natural Science or 0 years with a related Master’s Degree. Research Associate III Requirements noted for RA I plus: 3+ years of relevant research experience with a Bachelor’s Degree in Biological or Natural Science or 1 year relevant research experience with a related Master’s Degree Research Associate IV Requirements noted for RA I plus: 5+ years of relevant research experience with a Bachelor’s Degree in Biological or Natural Science or 3+ years relevant research experience with a related Master’s degree. Additional Information The focus of the Wolfe Laboratory is the development of genome editing tools, such as base editors and prime editors, to employ as new classes of therapeutics. The successful candidate would be a part of an interdisciplinary team of laboratory scientists, clinicians, and computational biologists that are working on therapeutics for a variety of neurological and neuromuscular disorders, as well as cancer. We are looking for a candidate that would be a key player in developing and characterizing novel genome editing systems that could serve as new therapeutics – with these reagents potentially being used in clinical trials. Experience Required: Basic molecular biology techniques (PCR, cloning, gel electrophoresis, plasmid purification). Mammalian Cell culture experience. Experience Desired (not required): Genome editing Illumina Sequencing library preparation Experience using mouse disease models Major Responsibilities (in addition to the standard set) : Participate in the development and characterization of genome editing systems tailored to correct gene mutations common in certain patient populations or kill cancer cells. Participate in the application of these genome editing systems in relevant mouse disease models. Organize ordering and stocking of supplies and reagents for the laboratory. Lab information https://www.umassmed.edu/Wolfe-Lab/ Options Apply for this job online Apply Share Refer this job to a friend Refer Sorry the Share function is not working properly at this moment. Please refresh the page and try again later. Share on your newsfeed Posting Disclaimer: This job posting outlines the primary responsibilities and qualifications for the role but is not intended to be an exhaustive list. Duties and expectations may evolve in response to the needs of the department and the broader institution. In alignment with our commitment to pay transparency, the base salary range for this position is listed above (exclusive of benefits and retirement). At UMass Chan Medical School, final base salary offers are determined based on a combination of factors, including your skills, education, and relevant experience. We also consider internal equity to ensure fair and consistent compensation across our teams. Please note that the range provided reflects the full base salary range for this position. Offers are typically made within the midrange to allow for future growth and development within the role. In addition to base pay, UMass Chan offers a comprehensive Total Rewards package, which includes paid time off, medical, dental, and vision coverage, and participation in a 401(a) retirement plan, with the option to contribute to a voluntary 403(b) plan. UMass Chan welcomes all qualified applicants and complies with all state and federal anti-discrimination laws. Application FAQs Software Powered by ICIMS www.icims.com