Scientist, In Vivo Cancer Modeling

Cloverleaf Bio

Boston, MAOn-siteFull time
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Location
Boston, MA
Work style
On-site
Job type
Full time
Posted
Oct 5
14 days ago
Career path

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About the company

Cloverleaf Bio

Biotechnology · 2 to 10 employees

About Us Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered RNA therapeutics.

Cloverleaf Bio on LinkedIn

What you'll do

  • Design and execute in-house mouse experiments; plan and coordinate toxicity, pharmacology, and efficacy studies at CROs.
  • Perform in vitro experiments to characterize candidate RNAs and provide in vivo pharmacology and physiology expertise.

What you need

  • Requires a PhD in Cancer Biology, Molecular Biology, or a related field; hands-on experience with mouse disease models, tissue collection and processing, and routine drug administration.
  • Education: a postgraduate degree

Key skills

mouse models of diseasetissue collection and processingintravenous and subcutaneous injectionsin-vivo studiesdata analysis and interpretationmammalian cell culturemolecular biology techniquesflow cytometryIHCELISARNA biochemistryprotein biochemistryRNA therapeuticslipid nanoparticles

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Perks

  • strong equity incentives
  • Medical, dental, and vision coverage
  • 401k retirement
  • employer match

See full description on company page, apply now

Read the full posting here
About Us Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered RNA therapeutics. The Job We are seeking an experienced in vivo Scientist to join our team. In this position, you will work in close conjunction with our founding team in the creation and development of a completely novel family of RNA therapeutics. Your responsibilities will include designing and executing in house animal experiments in mice, proposing, planning and coordinating toxicity, pharmacology and efficacy studies at CROs, performing in vitro experiments to characterize the mechanism and potency of candidate RNAs, and providing in vivo pharmacology and physiology expertise to accelerate development of our tRNA therapeutics. When & Where Location: Boston, MA Work Model: Full-time onsite About You Excited by the science. We are excited by how science can improve the world and are looking for people who are too. Flexible. We wear many different hats and are looking for people who are willing to do whatever it takes to pitch in and get the job done. Resilient. Working in an early-stage startup can be hard. Science is hard. We are looking for people who have a demonstrated track record of sticking with complex problems for the long haul. Cooperative. As a small team, communication and collaboration are key. We are looking for people who thrive working both independently and collaboratively. Qualifications: PhD in Cancer Biology, Molecular Biology, or related fields. Must have hands-on experience with mouse models of disease (preferably oncology), tissue collection and processing, and routine drug administration including intravenous and subcutaneous injections. Demonstrated ability to independently plan and execute in-vivo studies, data analysis and interpretation. Skilled in mammalian cell culture and molecular biology techniques. Nice to haves: Strong molecular/cell biology experience, particularly in immunology, RNA biochemistry and/or protein biochemistry. Hands-on experience with flow cytometry, IHC, ELISA. Experience with design/development RNA therapeutics and lipid nanoparticles. Previous experience selecting and overseeing work at CROs. Benefits: Competitive salary commensurate with experience and strong equity incentives. Medical, dental, and vision coverage. 401k retirement including employer match. A stimulating, collegial, and fast-paced environment.

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