Staff Research Associate

UCSF

San Francisco, CAOn-siteFull time
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Pay
$30
an hour
Location
San Francisco, CA
Work style
On-site
Job type
Full time
Posted
Oct 16
1 day ago
Career path

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About the company

UCSF

Hospitals and Health Care · 501 to 1,000 employees

The Department of Anesthesia and Perioperative Care at UC San Francisco is a pioneering leader in providing outstanding, state of the art healthcare that is equitable and inclusive. In alignment with the wider UCSF mission to advance health worldwide, we are committed to optimizing perioperative outcomes, training the next generation of anesthesiology leaders, and translating discoveries to benefit the health and life of our patients and the wide range of communities we serve. Consistently ranked in the top ten nationally in NIH-funded research, important discoveries by our department include the first use of CPAP in premature infants, key contributions to the pharmacology of muscle relaxants and inhaled anesthetics, first demonstration of intraoperative transesophageal echocardiography, and many others [https://anesthesia.ucsf.edu/anesthesia-timeline-fullscreen]. We have robust research programs, spanning the range from ion channel structure and function, to clinical and translational research [https://anesthesia.ucsf.edu/welcome-ucsf-anesthesia-research]. Our trainees have become leaders across the country. We are particularly proud of our residency program [https://anesthesia.ucsf.edu/education-program-ucsf-department-anesthesia], which provides unequaled diversity of experience in a major university medical center (UCSF Helen Diller Medical Center at Parnassus Heights), the San Francisco Veterans Hospital, Zuckerberg San Francisco General Hospital, Mount Zion Hospital, the UCSF Orthopaedic Institute, and the UCSF Benioff Children's, Betty Irene Moore Women's and Bakar Cancer (NIH-designated Cancer Center) Hospitals in the Mission Bay neighborhood. We offer ACGME fellowships in Critical Care Medicine, Pain Medicine, Cardiac Anesthesia, Obstetric Anesthesia, Pediatric Anesthesia, Acute Pain and Regional Anesthesia, and many additional non-ACGME fellowships. Our faculty are dedicated to teaching, nurturing, and mentoring the next generation of leaders.

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What you'll do

  • The Staff Research Associate will perform histological studies, including RNAscope and immunostaining, to investigate adrenergic receptor signaling in the gut.
  • They are responsible for data acquisition, statistical analysis, and the preparation of figures and summaries for lab meetings and publications.

What you need

  • Candidates must hold a Bachelor's degree in biological sciences or a related field.
  • Familiarity with molecular biology, neuroscience, and histological techniques is preferred.
  • Education: a bachelor's degree

Key skills

HistologyRNAscopeImmunostainingConfocal microscopyFluorescence microscopyImageJFijiQuPathGraphPad PrismRPythonStatistical analysisMolecular biologyNeuroscienceData quantificationLaboratory organization

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Read the full posting here
Job Summary  The Physiology Department is hiring for a  Staff Research Associate. The Staff Research Associate I will provide support for histological studies in the gut. The  Staff Research Associate I will work closely with lab members to carry out experiments and analyze data. RESPONSIBILITIES %  of time Essential Function (Yes/No)    Key Responsibilities (To be completed by Supervisor) 40 yesUnder supervision, perform experiments with mice to study the role of adrenergic receptor signaling in the gut in stress-induced visceral pain. Perform RNAscope in situ hybridization and related immunostaining on intestinal and related tissues, including tissue collection, fixation, sectioning, staining, and imaging. Responsible for the full data workflow for the experiments, including choosing appropriate statistical tests (e.g., t-tests, ANOVA, or nonparametric equivalents) for RNAscope quantification data, performing the calculations in GraphPad Prism or R, compiling results across animals and conditions, and preparing figures and tables for lab meetings and manuscripts.  20 yesAcquire images using brightfield, fluorescence, and confocal microscopy; perform image processing and quantification (e.g., ImageJ/Fiji, QuPath) 20 yesAnalyze and organize experimental data, generate figures and summary statistics (e.g., Excel, GraphPad Prism, R or Python), and present results at lab meetings.  20 yesMaintain detailed lab notebooks, prepare reagents and solutions, and help with general lab organization and ordering. Draft written summaries of experimental rationale, methods, results, and preliminary interpretations, which the principal investigator reviews and incorporates into presentations, grant reports, and publications. 100  (To update total %, enter the amount of time in whole numbers (without the % symbol - e.g., 15, 20) then highlight the total sum (e.g., 1%) at the bottom of the column and press F9. The total sum should add up to 100%.)     QUALIFICATIONS Required Qualifications: BA/BS in biological sciences or a related science and knowledge of, or experience with, the basic techniques or methods required by the position; and/or an equivalent combination of education and experience Preferred Qualifications: Familiarity with basic concepts in molecular biology and neuroscience. Familiarity with basic methodologies for assessing gene expression by histological techniques.

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